I would like to add, on top of all the common 15% vs 10% + Nightfall, that DS/Ruin has some neat utility talents that are often overlooked :
- 1440 health stones instead of 1200 ;
- +30% Stamina from Blood Pact's Imp's Buff. Agreed, you're not supposed to have your imp out since you usually sacrifice, but there is some fight you usuauly have an imp bitch because it's needed
- +15% stamina
- Sacrifice is not only about +15% shadow damage. You also have +15% fire (godlike in AQ) and the HP/Mana regen. You don't use them that often, but it's very handy to farm and has its uses in some PvE encounters.